Abstract
Background:
Human transform
nukleosida main purin, adenosine, and guanine into uric acid.
Because uric acid is a compound that
difficult to dissolve in water, so, to change a
compound that is easily dissolved in water required an enzyme urikase.
Hyperuricemia is a condition where the blood uric acid level is above normal.
Hyperuricemia is known that can be harmful because it can cause gout disease, nefrolithiasis. One of risk
factor of hyperuricemia is obesity. Obesity circumstances, may be increasing
prevalence of disease such as kardiovaskular disease, which are associated with
metabolic syndrome that one of them is hiperurisemia.
Objectives:
Understand the correlation between body mass index and the increase of uric
acid in blood.
Methods:
Type of research is descriptive research non-experimental research design with
"cross-sectional study". Data analysis will be done with an SPSS 15 program
with Spearman non-parametric correlation method. Research is the subject of men
in the area of Golo with IMT> 29 kg/m2 aged 22-48 years. The amount of
sample is taken as 20 people. Subjects are asked to fill the inform consent,
and in measuring body weight and height body, blood pressure and the last measure
is the uric acid content in blood using tools that have been provided.
Result:
From the 20 subjects examined, 10 person (50%) are obesity and 10 person (50%)
are non obesity, while the number of
hyperuricemia, of which 20 subjects examined, there were 9 people (45%). From
hyperurisemia of 9 people, 6 people (30%) are obesity, and 3 people (15%) are
non obesity. Analysis of test results using Spearman non-parametric correlation
and Sugiyono correlation strength table showed closeness correlation between obesity
and hyperuricemia (sig 0.025, correlation coefficient 0.500).
Conclusion:
there is closeness correlation between obesity
and hyperuricemia.
Keyword:
obesity, hyperuricemia
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