Abstract
The
aim of this study is to know the effect of cinnamon powder (Cinnamon burmani ) given to the blood glucose in alloxan-induced diabetic rats. Cinnamon powder contain flavonoid as antioxidant and MHCP
(methylhydroxy-chalcone
polymer) which provide hypoglycemic effect to reduce level blood glucose.
Eighteen males Rattus norvegicus rat were used throughout the study, and
randomly selected. The animals were divided into three groups, each group were
6 rats. The first group were not given anything, the second group were given
cinnamon powder 3,6 mg/day and the third were given cinnamon powder 7,2 mg/day. Rats in group 2 and 3 were given cinnamon powder everyday for 21 days.
Hypoglycemic activity was evaluated at day 0, 7, 14 and 21. The data was
compared statistically using one-way analysis of variance (ANOVA) followed by
post-hoc test Tukey HSD and paired sample t-test. The result indicated that
cinnamon powder giving significant effect on the reduction of blood glucose. In
this research were used the optimum doses to decreasing blood glucose level at
7,2 mg/day after 21 days treatment The double doses can not also decreasing speed of blood glucose causes.
Key words :
Cinnamon burmani, blood glucose, MHCP, flavonoid
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