Abstract
The coconut oil proved as an
antibacterial, antifungal, antiprotozoa, antioxidant and has effect on
epithelialization. The process of wound healing wereneeded epithelialization,
kolagenitation and prevent infection. This research was an experimental
research which conducted to prove coconut oil effect on the histological properties
on thermal burn healing.
The design research is experimental, in
vivo, using 30 female Sprague Dawley rats divided into six groups (control
without treatment, control Bioplacenton ®, factory VCO, home industry VCO, RBD
oil, and traditional coconut oil). Thermal burns were inducedand wounds are
given with 0.1 ml test material every day. After the wound healed, the skin
tissue is made preparations stained with HE and Mallory, and epithelial
thickness observed data, the number of fibroblasts and collagen density. Data
of epithelialization were analyzed with ANOVA test followed by Tukey anddata of
density of collagen and fibroblast were analyzed with Kruskal-Wallis test
followed by Mann Whitne.
The research indicated that the thickest
epithelial is RBD oil (225.8 ± 29.97%) with a value of
significance (p = 0.000). The largest number of fibroblasts is the large scale
industries VCO (139.1 ± 30.21 cells) with a value of significance (p = 0.000).
The most density collagen is home industry VCO (3.3 ± 1.08) with a value
of significance (p = 0.0000). This study proves that RBD oil effect on epithelialization, large scale
industries VCO effect on fibroblast count, home industry VCO effect on density
of collagen.
Keyword : coconut oil, thermal wound, epithelialization,
kolagenitation, fibroblast.
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